Best Practices for Collecting Physiological Data

This document is a work in progress. Currently, an outline of important topics is presented.

Why collect physiological data?

  • Physiological fluctuations can be treated as noise in fMRI data or as signals of interest to characterize different physiological states

  • Add regressors in the modeling of fMRI data to explain signal variance

    • Especially cardiac and respiratory effects as they can influence in the BOLD signal

  • Cardiac pulsatility and breathing related chest/abdomen movement –> RETROICOR

  • Monitor subject/patient during the scan (important during first-time scans, or breathing tasks)

What are the different types of physiological data that can be collected?

  • CO2& O2: specifically end-tidal pressures of CO2 and O2, which approximate the arterial levels of these gases

  • Cardiac pulsation: heart rate trace

  • Respiration: change in chest volume

How to collect each type of physiological data?

  • CO2 & O2: nasal cannula or face mask with gas analyzers, RespirAct (more specifically if you want to modulate end-tidal values)

  • Pulse: photo-plethysmograph, pulse oximeter

  • Respiration: respiratory belt, respiratory chest bellows

What to do with physiological data once it has been collected?

  • Use phys2bids to organize the data

  • Can also plot each channel from LabChart file the quickly view which kind of physiological data each channel represents

  • Use a peak detection algorithm to get end-tidal CO2 trace for breathing task BOLD fMRI and convolve with HRF

  • Use a peak detection algorithm to get HR trace and convolve with CRF

  • Use a peak detection algorithm to get respiratory trace and convolve with RRF

    • Perform RETROICOR on the cardiac and respiratory cycles to include in the GLM as regressors